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Pfizer says an early peek at its vaccine data suggests the shots may be 90% effective at preventing COVID-19. Monday's announcement doesn't mean a vaccine…

NPR's A Martinez talks with Republican strategist Alex Conant about what Florida's new migrant detention facility — dubbed "Alligator Alcatraz" — reveals about Trump's immigration strategy.

A pregnant woman and her baby have died after Russian forces shelled a maternity ward in Mariupol.

"We are back in the business of stealing secrets," says CIA chief Mike Pompeo, who made the comment Tuesday night in a session at CIA headquarters in northern Virginia. We examine what he meant.

Twelve more passengers were injured in the crash 15 miles north of New York City. It's the second major accident in 15 months for the Metro-North rail line, which serves 280,000 passengers a day.

NPR's Audie Cornish talks to Frederic Hof, director of the Atlantic Council's Rafik Hariri Center for the Middle East, about what shape the U.S. strategy in Syria will take after the military action in response to the Assad regime's use of chemical weapons.

The Justice Department said it would move to dismiss a lawsuit originally filed against Idaho by the Biden administration, according to court papers filed by the state's largest hospital network.

Scott Jennings, a political consultant and former GOP administration official, says that House Speaker Paul Ryan's retirement suggests to Republicans they should focus on holding on to the Senate.

President Obama defended a limited three-year resolution saying the country is not benefited "by being on a perpetual war footing."

Also: Pro-Syrian fighters kill dozens of civilians in heavy bombardments; potential flooding may come to the central U.S. today; and students will lobby for gun control at the Florida state capitol.