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The virus is the enemy, NIH Director Francis Collins said. "It's not the other people in the other political party." Omicron, which could soon become the dominant strain, is extremely infectious.

Paul Rudd hosted Saturday Night Live's last episode of the year, with no live audience and a limited cast and crew. It's not the first time the show has had to adapt to the coronavirus pandemic.

Democratic West Virginia Senator Joe Manchin went on Fox News this morning and delivered what sounded like a fatal blow to Joe Biden's Build Back Better agenda.

When the winner was announced, Emma Broyles was sure it was a mistake: "I said, 'No way. Are you sure? Do you want to check that card again?' "

NPR's Scott Simon reflects on "The Virgin and Child with a Flower on a Grassy Bank," by Renaissance artist Albrecht Dürer. The previously unknown drawing was unveiled this week in London.

NPR's Sacha Pfeiffer speaks to Imran Amed, fashion writer and CEO of The Business of Fashion, about the future of the fashion industry in a virtual world.

NPR's Sacha Pfeiffer speaks with UCLA Law Professor Jon Michaels about the trend of laws designed to roll back certain protected rights through private citizen enforcement.

NPR's Sacha Pfeiffer speaks with director Adam McKay about his newest film, Don't Look Up.

NPR's Sacha Pfeiffer speaks with Odile Schalit, executive director of the abortion support services group The Brigid Alliance, about how her work has changed since the passage of SB 8.

We asked for your questions on navigating the holiday blues. Clinical psychologist Andrea Bonior guides us through some rough patches involving family, money, loneliness and safety.